Alprazolam (XANAX)
CAS Number:
28981 – 97 – 7
Batch Molecular Formula:
C17H13ClN4
Batch Molecular Weight:
308.77 g·mol
Physical Appearance:
White Solid Powder
Solubility:
Insoluble in Water
Storage:
Store at RT
Alprazolam API (Xanax) is a prescription benzodiazepine primarily used to treat anxiety disorders and panic disorders, as well as anxiety associated with depression. It works by acting on the central nervous system to produce a calming effect. Alprazolam may also be used in certain off-label applications, including short-term management of insomnia, muscle tension, and chemotherapy-related nausea.
Alprazolam formulations can be categorized based on their medical applications and characteristics:
1. Key Uses and Indications
Panic Disorder: Used with or without agoraphobia and approved for the short-term management of severe, abrupt panic attacks.
Anxiety Disorders: Used in the treatment of generalized anxiety disorder (GAD) and anxiety associated with depression.
Off-Label Applications: May be used under medical supervision for short-term insomnia, premenstrual syndrome, and chemotherapy-associated nausea.
2. Mechanism of Action
GABA Receptor Activity: Alprazolam acts on the GABA receptor complex, increasing inhibitory neurotransmission and helping reduce excessive brain activity.
Calming Effect: Its central nervous system activity contributes to its anxiolytic and sedative effects.
3. Effectiveness and Safety Considerations
Clinical Use: Clinical studies evaluating alprazolam for anxiety disorders have generally been limited to approximately four months.
Controlled Substance: Alprazolam is a controlled substance with potential for dependence, addiction, and misuse.
Common Side Effects: Reported side effects include drowsiness, lightheadedness, and cognitive impairment, with increased sensitivity possible in elderly patients.
Axim Pharma – Alprazolam API Manufacturer & Contract Manufacturer in India
Axim Pharma is a trusted Alprazolam API manufacturer and contract manufacturer in India, serving pharmaceutical customers across China, Turkey, Hong Kong, the USA, Europe, and other international markets. We offer custom manufacturing, bulk API supply, competitive pricing, and seamless logistics tailored to your requirements.
Partner with Axim Pharma for high-quality Alprazolam API production, custom synthesis, bulk supply, and global distribution, supporting consistent quality and compliance with applicable requirements across international markets.
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Effects
1. Therapeutic Effects
Reduced Anxiety: Helps relieve symptoms associated with anxiety disorders and generalized anxiety disorder (GAD).
Reduced Panic Symptoms: Helps reduce the frequency and severity of panic attacks in individuals with panic disorder.
Calming Effect: Produces a calming effect by reducing excessive activity in the central nervous system.
Muscle Relaxation and Sedation: May produce muscle-relaxant and sedative effects as a result of its central nervous system activity.
2. Common Side Effects
Drowsiness: May cause sleepiness and reduced alertness.
Dizziness or Lightheadedness: Can affect balance and coordination.
Cognitive Effects: May cause impaired concentration, memory difficulties, or slowed thinking.
Fatigue: May contribute to tiredness or reduced energy levels.
3. Serious Risks
Dependence and Withdrawal: Prolonged use can lead to physical dependence, with potentially serious withdrawal symptoms if stopped abruptly.
Misuse and Addiction: Alprazolam is a controlled substance with potential for misuse and addiction.
Respiratory Depression: The risk can increase significantly when combined with opioids, alcohol, or other central nervous system depressants.
Impaired Coordination: Sedation and impaired motor skills may increase the risk of accidents and falls.
Usage
. Primary Uses
Anxiety Disorders: Used for the treatment of generalized anxiety disorder and anxiety associated with depression.
Panic Disorder: Used for the management of panic disorder, with or without agoraphobia.
Short-Term Anxiety Management: Generally prescribed for short-term treatment where clinically appropriate.
2. Mechanism of Action
Alprazolam is a benzodiazepine that acts on the GABA-A receptor complex in the central nervous system. It enhances the effects of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which reduces excessive neuronal activity and produces anxiolytic, sedative, and muscle-relaxant effects.
Disclaimer
Products falling in to controlled substance category / list of schedule drugs shall be exported directly from the manufacturer principals only against receipt of original import permission issued by concerned authorities of the importing country. Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer’s risk. Most OTC drugs are not reviewed and approved by FDA, however, they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies. This is only for study not for any Human / Veterinary use. (Condition Apply)* Axim Pharmaceutical India warns the buyers / importers not to use/sell/procure any goods to achieve a product which might be knowingly causing an infringement / controlled / banned drugs. Axim Pharmaceutical India is not responsible or liable for the same.
