Methadone HCL
CAS Number:
1095–90-5
Batch Molecular Formula:
C21H27NO
Batch Molecular Weight:
309.445 g/mol
Physical Appearance:
White Crystalline Solid / Powder
Solubility:
Very Soluble in Water
Storage:
Store at RT
Methadone API is a long-acting synthetic opioid primarily used for pain management and opioid use disorder (OUD) treatment. It is a controlled substance due to its potential for abuse and dependence. When used appropriately under medical supervision, methadone is a highly effective medication.
Methadone formulations can be systematically categorized into three primary classifications:
1. Medical Formulations
Tablets: Available in different strengths, including 5 mg and 10 mg.
Oral Solutions: Commonly used in opioid use disorder (OUD) treatment, including formulations such as Methadose.
Injectable Form: Used in hospital settings for severe pain and specific clinical applications.
2. Immediate-Release Methadone
Pain Management: Provides relatively rapid relief for severe pain under medical supervision.
Acute Medical Settings: Used when immediate opioid analgesia is clinically indicated.
3. Long-Acting Methadone
Maintenance Therapy: Used in medically supervised treatment for opioid use disorder.
Once-Daily Administration: Its long half-life supports once-daily dosing in appropriate treatment settings.
Axim Pharma – Methadone API Manufacturer & Contract Manufacturer in India
Axim Pharma is a trusted methadone API manufacturer and contract manufacturer in India, serving customers across international markets. We offer custom manufacturing, bulk API supply, competitive pricing, and seamless logistics tailored to your requirements.
Partner with Axim Pharma for high-quality methadone API production, custom synthesis, bulk supply, and global distribution, supporting consistent quality and compliance with applicable requirements.
Contact our sales team today for personalized quotations and efficient delivery solutions.
Effects
1. Therapeutic Effects
Relieves pain by acting on opioid receptors in the CNS.
Suppresses opioid withdrawal symptoms and cravings.
Stabilizes individuals with OUD, allowing for normal functioning.
2. Side Effects
Common:
Drowsiness, dry mouth, and sweating.
Nausea, vomiting, and constipation.
Serious:
Respiratory depression (potentially life-threatening).
QT prolongation (risk of arrhythmias).
Physical dependence with long-term use.
Usage
1. Medical Use
Opioid Use Disorder (OUD):
Maintenance therapy to prevent withdrawal symptoms and reduce cravings.
Reduces the risk of overdose and transmission of infectious diseases (e.g., HIV, hepatitis) by discouraging illicit opioid use.
Chronic Pain Management:
Prescribed for severe pain unresponsive to other medications, especially in cancer or palliative care.
2. Non-Medical Use
Occasionally misused for its sedative and euphoric effects.
Disclaimer
Products falling in to controlled substance category / list of schedule drugs shall be exported directly from the manufacturer principals only against receipt of original import permission issued by concerned authorities of the importing country. Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer’s risk. Most OTC drugs are not reviewed and approved by FDA, however, they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies. This is only for study not for any Human / Veterinary use. (Condition Apply)* Axim Pharmaceutical India warns the buyers / importers not to use/sell/procure any goods to achieve a product which might be knowingly causing an infringement / controlled / banned drugs. Axim Pharmaceutical India is not responsible or liable for the same.









