Sibutramine HCL
CAS Number:
106650-56-0
Batch Molecular Formula:
C17H26ClN
Batch Molecular Weight:
279.85 g/mol
Physical Appearance:
White to Off White Crystalline Powder
Solubility:
Soluble in Water
Storage:
Store at RT
Sibutramine hydrochloride (HCl) API is a medication that was primarily used as an appetite suppressant for weight management. It acts on the central nervous system to promote satiety, helping individuals consume fewer calories. Although it was used for weight management, its use has been discontinued or restricted in many countries due to concerns about cardiovascular risks.
Sibutramine HCl formulations have included the following branded products:
Original Sibutramine HCl Formulations
Meridia: Previously marketed in the United States.
Reductil: Previously marketed in Europe.
Sibutrex: A brand associated with sibutramine formulations in certain markets.
Other Formulations: Sibutramine has been marketed under various brand names and formulations in different countries.
Axim Pharma – Sibutramine HCl API Manufacturer & Contract Manufacturer in India
Axim Pharma is a trusted Sibutramine HCl API manufacturer and contract manufacturer in India, serving pharmaceutical customers across China, Turkey, Hong Kong, the USA, Europe, and other international markets. We offer custom manufacturing, bulk API supply, competitive pricing, and seamless logistics tailored to your requirements.
Partner with Axim Pharma for high-quality Sibutramine HCl API production, custom synthesis, bulk supply, and global distribution, supporting consistent quality and compliance with applicable requirements across international markets.
Contact our sales team today for personalized quotations and efficient delivery solutions.
Effects
1. Positive Effects
Reduced appetite and caloric intake.
Modest weight loss when combined with lifestyle changes.
Improved metabolic markers in some individuals.
2. Negative Effects
Common Side Effects:
Dry mouth, headache, constipation, and insomnia.
Increased heart rate and blood pressure.
Severe Side Effects:
Cardiovascular risks, including heart attack and stroke.
Mood changes, anxiety, and potential for serotonin syndrome.
Usage
1. Primary Use
Obesity Management: Prescribed to aid in weight loss for individuals with a body mass index (BMI) ≥30 kg/m² or ≥27 kg/m² with obesity-related conditions (e.g., diabetes, hypertension).
Functioned as part of a comprehensive weight-loss plan, including diet and exercise.
2. Mechanism of Action:
Sibutramine inhibits the reuptake of serotonin, norepinephrine, and dopamine, increasing their levels in the brain. This enhances feelings of fullness and reduces appetite.
Disclaimer
Products falling in to controlled substance category / list of schedule drugs shall be exported directly from the manufacturer principals only against receipt of original import permission issued by concerned authorities of the importing country. Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer’s risk. Most OTC drugs are not reviewed and approved by FDA, however, they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies. This is only for study not for any Human / Veterinary use. (Condition Apply)* Axim Pharmaceutical India warns the buyers / importers not to use/sell/procure any goods to achieve a product which might be knowingly causing an infringement / controlled / banned drugs. Axim Pharmaceutical India is not responsible or liable for the same.
